| 02.02.1966 | SL Benfica | 3 | - | 2 | W | 64.035 | ECup | QF-1 | H | Old Trafford | David Herd 37', Denis Law 42', Bill Foulkes 6 ' | ||||
| 09.03.1966 | SL Benfica | 5 | - | 1 | W | 75.000 | ECup | QF-2 | U | Estadio da Luz | George Best 6', 13', John Connelly 16', Pat Crerand 8 ', Bobby Charlton 89' | ||||
| 29.05.1968 | SL Benfica | 4 | - | 1 | W | 100.000 | ECup | F | aet | N | Wembley | Bobby Charlton 53', 99', George Best 92', Brian Kidd 93' | |||
| 27.09.2005 | SL Benfica | 2 | - | 1 | W | 66.112 | ECup | grD | H | Old Trafford | Ryan Giggs 39', Ruud van Nistlerooy 85' | ||||
| 07.12.2005 | SL Benfica | 1 | - | 2 | L | 65.000 | ECup | grD | U | Estadio da Luz | Paul Scholes 6' | ||||
| 26.09.2006 | SL Benfica | 1 | - | 0 | W | 61.000 | ECup | grF | U | Estadio da Luz | Louis Saha 60' | ||||
| 06.12.2006 | SL Benfica | 3 | - | 1 | W | 74.955 | ECup | grF | H | Old Trafford | Nemanja Vidic 45', Ryan Giggs 61', Louis Saha 75' | ||||
| 14.09.2011 | SL Benfica | 1 | - | 1 | D | 59.671 | ECup | grC | U | Estadio da Luz | Ryan Giggs 42' | ||||
| 22.11.2011 | SL Benfica | 2 | - | 2 | D | 74.853 | ECup | grC | H | Old Trafford | Dimitar Berbatov 30', Darren Fletcher 59' | ||||
| 18.10.2017 | SL Benfica | 1 | - | 0 | W | 57.684 | ECup | GrA | U | Estádio da Luz | Marcus Rashford 64' | ||||
| 31.10.2017 | SL Benfica | 2 | - | 0 | W | 74.467 | ECup | GrA | H | Old Trafford | Mile Svilar 45' (o.g.), Daley Blind 78' (pen) |