| 10.10.2001 | Olympiakos Pireus | 2 | - | 0 | W | 73.537 | ECup | grG | U | Olympic Stadium | David Beckham 66', Andrew Cole 82' | ||||
| 23.10.2001 | Olympiakos Pireus | 3 | - | 0 | W | 66.769 | ECup | grG | H | Old Trafford | Ole Gunnar Solskjaer 80', Ryan Giggs 88', Ruud van Nistlerooy 90' | ||||
| 01.10.2002 | Olympiakos Pireus | 4 | - | 0 | W | 66.902 | ECup | grF | H | Old Trafford | Ryan Giggs 19', Juan Sebastian Veron 26', Georgios Anatolakis (o.g.) 67', Ole Gunnar Solskjaer 77' | ||||
| 23.10.2002 | Olympiakos Pireus | 3 | - | 2 | W | 13.220 | ECup | grF | U | Rizoupoli | Laurent Blanc 20', Juan Sebastian Veron 58', Paul Scholes 83' | ||||
| 25.02.2014 | Olympiakos Pireus | 0 | - | 2 | L | 29.815 | Ecup | R2-1 | U | Karaiskakis Stadium | |||||
| 19.03.2014 | Olympiakos Pireus | 3 | - | 0 | W | 74.662 | ECup | R2-2 | H | Old Trafford | Robin van Persie 25' (pen), 45', 51' |